The defective mismatch repair system may result in mutations of genome and cause tumors.

错配修复系统缺陷可能导致遗传物质发生突变，引发恶性肿瘤。

But the large loop repair, a distinct repair from mismatch repair, is an unknown repair system.

但是大型核酸环的修复，一个迥异于配对错误的修复机制，却是个未知的系统。

This paper reviewed the relationship between DNA mismatch repair, chromosome instability and cancer.

本文就DNA错配修复、染色体不稳定和肿瘤之间的联系予以综述。

In several but not all cases, mutators have been found to contain defects in mismatch repair (MMR) pathways;

在一些但不是所有情况下，存取器已被发现含有缺陷的错配修复（MMR）途径；

When function defects of mismatch repair genes, Cell Showes Genomic instability because of the aggregation of mutation.

错配修复基因功能缺失时，细胞常会因基因突变聚集而表现为遗传不稳定。