-
The content of etoposide injection was determined by first order derivative spectrophotometry.
用一阶导数光谱法测定足叶乙甙注射液的含量。
-
To study the possibility and the mechanism of K562 apoptosis induced by microwave and etoposide.
探讨微波和足叶乙苷体外诱导K562 细胞凋亡的可能性及其机制。
-
The pretreatment regimen was Cytarabine, Etoposide, Cyclophosphamide and total body irradiation.
预处理选用阿糖胞苷、足叶乙苷、环磷酰胺和全身照射。
-
The result showed that the percentage of apoptosis cell increases with the time of exposure to etoposide.
结果显示,凋亡细胞的百分比随诱导时间的延长而逐渐增多。
-
OBJECTIVE: to evaluate the efficacy of etoposide and to explore its new indications in combined chemotherapy.
目的:验证拉司太特胶囊的临床疗效和探索一些新的适应症如治疗非小细胞肺癌、食管癌等。
依托泊苷为细胞周期特异性抗肿瘤药物,作用于DNA拓扑异构酶Ⅱ,形成药物-酶- DNA稳定的可逆性复合物,阻碍DNA修复。实验发现这复合物可随药物的清除而逆转 ,使损伤的DNA得到修复,降低了细胞毒作用。因此,延长药物的给药时间,可能 提高抗肿瘤活性。 2017年10月27日,世界卫生组织国际癌症研究机构公布的致癌物清单初步整理参考,依托泊苷与顺铂和博来霉素合用在一类致癌物清单中。