I'm sick and tired of your moaning.

你的牢骚我都听腻了。

I'm sick and tired of all the arguments.

我对所有这些争论烦透了。

I am sick and tired of hearing all these people moaning.

我厌倦了听所有这些人抱怨个没完。

I'm sick and tired of my job.

我对我的工作厌透了，真想' '。

I'm sick and tired of him.

我对他已讨厌极了。