We cannot in all conscience refuse to help.

凭良心我们不能拒绝去帮助别人。

An unusual quiet possessed the village, although it was ordinarily quiet enough, in all conscience.

村子里有一种异乎寻常的安静，虽说实话，它平时也挺安静的。

He did poorly in English in all conscience.

凭良心说，他英语学得太差了。

You can't, in all conscience, ask him again.

说真的，你不能再问他了。

He couldn't do such a thing in all conscience.

从良心上来讲，他不能做这样的事。