She found him sleeping heavily, and all her efforts to awaken him were of no avail.

她发现他睡得很沉，她想唤醒他的一切努力都无济于事。

Now it's done, regrets are of no avail.; It's no use crying over spilt milk.

事已如此， 后悔也是枉然。

All his efforts were of no avail.

他的努力都没有用。

The advice we got was of no avail.

我们得到的这个建议根本没用。

The advice we got was of no avail.

我们得到的建议完全没用。