My handwriting was the despair of my teachers.

我的字写得很差，使老师们感到十分失望。

I despair of him; he can't keep a job for more than six months.

我对他都绝望了，他做任何工作都超不过半年。

If we can't bring our problems under control, feelings of powerlessness and despair often ensue.

如果我们不能将我们的问题控制住，无能为力和绝望感往往就会随之而来。

I leave you to think of the terrible grief, the shame, the despair of the poor Marionette.

你们想想可怜的木偶有多么伤心、羞愧和绝望！

I began to despair of my future.

我开始对前途感到失望。