These facts boil down to very little significance.

这些事实没有多大意义。

Lots of companies use abbreviated names or numbers for employee e-mail addresses and those abbreviations or numbers will mean little to someone not familiar with their significance.

许多公司使用员工姓名的缩写或数字作为其邮箱地址。 可是，这些缩写和数字对于陌生人毫无意义。

To us the impersonality of electronic communication has little or no relation to the significance of the matter at hand.

对于我们来说，电子通讯的非人性化与将要面对的问题的实质只有很少的联系，甚至毫无联系。

Can you talk a little bit about the significance of your laborious process and how you maintain momentum and focus?

你可以解释一下你在劳动过程中的意义与及你如何去维持你的焦点和动力吗？