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Objective To observe the significance of measuring the serum prostate specific antigen(PSA).
目的:观察血清前列腺特异性抗原(PSA)测定的意义。
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Objective To investigate the effect of prostate specific antigen (PSA) and levels of sex hormones as well as prostatic acid phosphatase (PAP) on prostatic size.
目的探讨前列腺特异性抗原(PSA)与性激素及酸性磷酸酶(PAP)在不同年龄组与前列腺体积的变化关系。
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Objective: To evaluate the diagnosis and prognosis value of serum prostate specific antigen(PSA) and prostate specific antigen density(PSAD) in patients with prostatic adenocarcinoma.
目的:探讨血清前列腺特异抗原(PSA)、前列腺特异抗原密度(PSAD)在前列腺癌诊断及预后判定中的价值。
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Objective:To study the relationship between the expression of pS2 protein, prostate specific antigen(PSA) and breast carcinoma with neuroendocrine (NE) cells differentiation.
目的:探讨雌激素调节蛋白(p S2 )、前列腺特异抗原(PSA)的表达与乳腺癌神经内分泌细胞(NE细胞)分化的关系。
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Methods Serum prostate specific antigen and free prostate specific antigen contents were determined before treatment and 1,3,6 months after treatment.
方法:测定前列腺癌患者内分泌治疗前及治疗后1,3,6个月血清前列腺特异抗原、游离前列腺特异抗原变化。
前列腺特异抗原(prostate specific antigen,PSA)是由前列腺上皮细胞分泌产生,属激肽酶家族蛋白,存在于前列腺组织和精液中,正常人血清中含量极微。前列腺特异抗原在血清中主要以三种形式存在:①游离前列腺特异抗原(fPSA),占总前列腺特异抗原(tPSA)的10%~30%;②前列腺特异抗原与α1-抗糜蛋白酶结合形成的复合物(PSA-ACT);③前列腺特异抗原与α2-巨球蛋白酶结合形成的复合物(PSA-α2M)。后两者又称复合前列腺特异抗原(cPSA)。前列腺特异抗原的主要生理功能是可防止精液凝固,具有极高的组织器官特异性,是目前诊断前列腺癌的首选标志物。